H antigen
(Redirected from Substance H)
H antigen can refer to one of the various types of antigens having diverse biological functions:
- Also known as substance H, H antigen is a precursor to each of the ABO blood group antigens, apparently present in all people except those with the Bombay Blood phenotype[1] (see hh blood group). The gene responsible for making H antigen is FUT1, located on the 19th chromosome in humans.
- Histocompatibility antigen, a major factor in graft rejection. Even when Major Histocompatibility Complex genotype is perfectly matched, can cause slow rejection of a graft.[2]
- major H antigens "encode molecules that present foreign peptides to T cells"[2]
- minor H antigens "present polymorphic self peptides to T cells".[2] Includes, e.g. the H-Y antigen
- a bacterial flagellar antigen[3]
This set index article includes a list of related items that share the same name (or similar names).
If an internal link incorrectly led you here, you may wish to change the link to point directly to the intended article.
If an internal link incorrectly led you here, you may wish to change the link to point directly to the intended article.
References
[edit]- ^ Science Of Biogenetics (18 December 2023). "Do you Know Bombay Blood Group".
- ^ a b c Janeway, Charles A. (2001). Immunobiology the immune system health & disease (5. ed.). New York: Garland. ISBN 978-0-8153-3642-6. Retrieved 16 December 2013.
- ^ Farlex. "antigen". The Free Dictionary. Retrieved 16 December 2013.
 | This immunology article is a stub. You can help Wikipedia by expanding it. |